Michael A. Berry received his M.D. degree from the University of Texas Southwestern Medical School in Dallas in 1971. After a general surgery internship in the United States Air Force, he spent four years as a fighter squadron flight surgeon in Spain and England. In 1976, he entered his residency in Aerospace Medicine at Ohio State University in Columbus, Ohio, and received his Master's Degree in Preventive Medicine in 1977.

In 1978, he was certified by the American Board of Preventive Medicine in Aerospace Medicine. Following his residency, he became the Chief of the Flight Medicine Clinic at the NASA Johnson Space Center in Houston, Texas, where he was responsible for the screening and selection of new astronauts and participated in the certification and training of astronauts for space flight. In addition to participating in the extensive medical preparations for the first flight of the Space Shuttle, he served as a member of the Flight Control Team for the first two flights of the Shuttle Columbia.

On leaving NASA in 1981, he entered the private practice of Aerospace Medicine with Preventive & Aerospace Medicine Consultants, in Houston, Texas where he was a consultant and FAA Aviation Medical Examiner for 25 years. During this time, he also served as an FAA Human Intervention Motivation Study (HIMS) trained AME monitoring many airline and corporate pilots during their recovery.

In 2006, Dr. Berry accepted a Senior Executive position with the Federal Aviation Administration in Washington, D.C. as the Manger, Medical Specialties Division at FAA Headquarters.

In March 2014, Dr. Berry was selected as the FAA Deputy Federal Air Surgeon. Dr. Berry has been a Senior Aviation Medical Examiner for the FAA since 1979, and an Aviation Medical Examiner for Transport Canada. He is a Fellow of the Aerospace Medical Association, and the American College of Preventive Medicine. He is a Past President of the Aerospace Medical Association, past Vice-President of the Civil Aviation Medical Association, and Past President of the International Academy of Aviation and Space Medicine (2009-2011).

He served as a Board Member and Trustee of the American Board of Preventive Medicine and as the Vice-Chair for Aerospace Medicine from 1990-1998. Dr. Berry is the recipient of numerous national awards, has several academic appointments, and authored many scientific papers and book chapters.