Guide for Aviation Medical Examiners

CACI Conditions

Conditions AMEs Can Issue (CACI) is a series of conditions which allow AMEs to regular issue if the applicant meets the parameters of the CACI Condition Worksheet. The worksheets provide detailed instructions to the examiner and outline condition-specific requirements for the applicant.

  1. Review the disposition table BEFORE the CACI worksheet to verify a CACI is required.
  2. If all the CACI criteria are met and the applicant is otherwise qualified, the AME may issue on the first exam or the first time the condition is reported to the AME without contacting AMCD/RFS. Document the appropriate notes in Block 60 and keep the supporting documents in your files; they do not need to be submitted to the FAA at this time.
  3. If the requirements are not met, the AME must defer the exam and send the supporting documents to the FAA.
CACI ConditionCACI Condition
Arthritis (PDF)Hypothyroidism
AsthmaLow Testosterone (Low T) Hypogonadism (PDF)
Bladder CancerMASH / NASH (Liver) (PDF)
Breast Cancer (PDF)Migraine and Chronic Headache (PDF)
Carotid /Vertebral Artery Stenosis (PDF)Mitral Valve Repair (PDF)
C-ITP (Chronic Immune Thrombocytopenia) (PDF)Polycystic Ovarian Syndrome (PCOS) (PDF)
Chronic Kidney DiseasePrediabetes (PDF)
Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) (PDF)Primary Hemochromatosis (PDF)
ColitisProstate Cancer
Colon Cancer/Colorectal Cancer (PDF)Psoriasis (PDF)
Eosinophilic Esophagitis (PDF)Renal Cancer
Essential Tremor (PDF)Retained Kidney Stone(s) (PDF)
GlaucomaTesticular Cancer
Hepatitis C – ChronicWeight Loss Management (PDF)
Hypertension 
Last updated: Wednesday, April 29, 2026