FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute

Report No: DOT/FAA/AM-63/01

Title and Subtitle: The development of reversible hematuria and oliguria following elevation of renal venous pressure

Report Date: January 1963

Authors: Emerson TE, Hinshaw LB, Brake CM, Iampietro PF

Abstract: An investigation was completed to study the acute effects of elevated renal venous pressure in the development of reversible gross hematuria and oliguria. Both isolated and intact dog kidney preparations were utilized. Results demonstrate that gross hematuria was produced as renal venous pressure was elevated, but not until a relatively high pressure was produced. The degree of hematuria increased as the pressure was further elevated but disappeared rapidly following restoration to control pressure. The effect of renal venous pressure elevation on urine flow rate was one of progressive oliguria after a critical pressure was reached, and eventually anuria at the highest pressure. This effect was also reversible.

Key Words: renal hemodynamics, renal function, hematuria

No. of Pages: 10