Aerospace Medicine Technical Reports

FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute


Report No: DOT/FAA/AM-63/04

Title and Subtitle: Problems in aerial application: II. Effects of chlorinated hydrocarbons on substrate-linked phosphorylation

Report Date: March 1963

Authors: Daughterty JW, Lacey DE, Korty P

Abstract: In a search for an explanation of an earlier finding that dieldrin decreased the rate of methionine uptake by cardiac muscle, chickens and rats were exposed to this compound and the substrate-linked phosphorylation phenomenon was studied during the anaerobic degradation of glucose. Exposure to dieldrin reduced the esterification of inorganic phosphate 50% but did not affect the production of lactic acid. Four other chlorinated hydrocarbons, lindane, heptachlor, isodrin, and endrin did not produce this effect.

Key Words: biochemical toxicology, crop dusting, civil aviation, insecticides

No. of Pages: 10

Last updated: Friday, June 1, 2012