FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute

Report No: DOT/FAA/AM-65/27

Title and Subtitle: Intrarenal hemodynamic changes following acute partial renal arterial occlusion.

Report Date: October 1965

Authors: Brake CM, Reins D, Wittmers LE, Hinshaw LB.

Abstract: Both an increase and a decrease in total renal vascular resistance, following a period of total renal artery occlusion, have been reported from this laboratory. The duration of the occlusive period and height of the perfusion pressure were found to prescribe consistently the hemodynamic response. The present study, using adult mongrel dogs, indicates that, following a period of partial occlusion, in a critical range of renal artery pressure (40% to 50% of control), intrarenal hemodynamic changes mimicked those seen after total obstruction of blood flow. Reactive hyperemia was not observed.

Key Words: kidneys, blood circulation, arteries, obstruction (physiology), blood pressure, response (biology), stress (physiology).

No. of Pages: 6