FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute

Report No: DOT/FAA/AM-66/05

Title and Subtitle: Problems in aerial application: A comparison of the effects of dieldrin poisoning in cold-adapted and room-temperature mammals.

Report Date: April 1966

Authors: Clark G.

Abstract: The effects of dieldrin poisoning on the liver were compared in cold-adapted rats and normal rats. One-fourth of the cold-adapted rats succumbed to the poisoning while all of the normal rats survived. There were minimal fat deposits in both groups, but the cold-adapted rats were least affected.

By contrast, cytoplasmic RNA was altered to a greater extent in the cold-adapted rats, although with both the changes were located periportally. Another stain that is probably specific for secondary amines was increased in both treated groups but was decreased in cold adaptation.
Key Words: poisoning, adaptation (physiology), insecticides, sprays, liver, phospholipids, acclimatization, ribonucleic acids, rats, pathology, halogenated hydrocarbons.

No. of Pages: 8