Office of Aerospace Medicine Technical Reports
FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute
Report No: DOT/FAA/AM-70/3
Title and Subtitle: Effects of an organophosphorus pesticide on reproduction in the rat
Report Date: January 1970
Authors: Ryan, LC, Endecott BR, Hanneman GD, Smith PW
Abstract: The toxic effects of organophosphorus insecticides are commonly ascribed to cholinesterase (CHE) inhibition. A search of the scientific literature revealed the well-established fact that a number of chlorinated pesticides adversely affect reproduction in mice and rats.
However, little is known about the effects of organophosphorus pesticides on reproduction. Disulfoton was selected for this study because it is a widely used organophosphorus insecticide for which the acutely toxic, nonlethal dose in rats has been established.
Key Words: Pesticide
No. of Pages: 7
Civil Aerospace Medical Institute
Report No: DOT/FAA/AM-70/3
Title and Subtitle: Effects of an organophosphorus pesticide on reproduction in the rat
Report Date: January 1970
Authors: Ryan, LC, Endecott BR, Hanneman GD, Smith PW
Abstract: The toxic effects of organophosphorus insecticides are commonly ascribed to cholinesterase (CHE) inhibition. A search of the scientific literature revealed the well-established fact that a number of chlorinated pesticides adversely affect reproduction in mice and rats.
However, little is known about the effects of organophosphorus pesticides on reproduction. Disulfoton was selected for this study because it is a widely used organophosphorus insecticide for which the acutely toxic, nonlethal dose in rats has been established.
Key Words: Pesticide
No. of Pages: 7
Last updated: Friday, June 1, 2012