Office of Aerospace Medicine Technical Reports
FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute
Report No: DOT/FAA/AM-70/4
Title and Subtitle: Studies on the storage stability of human blood cholinesterases: I
Report Date: January 1970
Authors: Crane CR, Sanders DC, Abbott JK
Abstract: Whole blood, red cell, and plasma preparations were stored at room temperature, refrigerated, and frozen. Samples were assayed over a 50-day period using the technique of constant-pH titration (pH-Stat). At least 90% of the cholinesterase activity in the whole blood and plasma preparations was retained for 6 days at room temperature and over 6 weeks when refrigerated or frozen. Red cell preparations retained 90% activity for less than 12 hours at room temperature, for up to 3 days if refrigerated, and up to 6 weeks when frozen.
Key Words: Blood--storage, Cholinesterase--blood, Enzymes, Stability, Analysis, PH factor, Temperature, Freezing, Organic phosphorus compounds, Insecitcides
No. of Pages: 11
Civil Aerospace Medical Institute
Report No: DOT/FAA/AM-70/4
Title and Subtitle: Studies on the storage stability of human blood cholinesterases: I
Report Date: January 1970
Authors: Crane CR, Sanders DC, Abbott JK
Abstract: Whole blood, red cell, and plasma preparations were stored at room temperature, refrigerated, and frozen. Samples were assayed over a 50-day period using the technique of constant-pH titration (pH-Stat). At least 90% of the cholinesterase activity in the whole blood and plasma preparations was retained for 6 days at room temperature and over 6 weeks when refrigerated or frozen. Red cell preparations retained 90% activity for less than 12 hours at room temperature, for up to 3 days if refrigerated, and up to 6 weeks when frozen.
Key Words: Blood--storage, Cholinesterase--blood, Enzymes, Stability, Analysis, PH factor, Temperature, Freezing, Organic phosphorus compounds, Insecitcides
No. of Pages: 11
Last updated: Friday, June 1, 2012