Office of Aerospace Medicine Technical Reports

FAA Office of Aerospace Medicine
Civil Aerospace Medical Institute


Report No: DOT/FAA/AM-83/4

Title and Subtitle: Some effects of smoking withdrawal on complex performance and physiological responses

Report Date: January 1983

Authors: Mertens HW, McKenzie JM, Higgins EA

Abstract: The effects of smoking withdrawal on complex (time-shared) performance and physiological responses were studied at a simulated aircraft cabin altitude of 6,500 ft. Seventeen habitual smokers, nine women and eight men 23 to 59 years of age, served as subjects.

Time-shared performance of monitoring, tracking, mental arithmetic, and problem solving tasks were measured by the Civil Aeromedical Institute (CAMI) Multiple Task Performance Battery (MTPB) in two 4-h test sessions, one in which smoking was permitted at 1/2-h intervals and a no-smoking session. Corollary physiological measurements involved urinary hormones (epinephrine, norepinephrine, and 17-ketogenic steroids), carboxyhemoglobin levels (COHb), and heart rate (HR).

Overall composite scores for MTB performance revealed decrements during withdrawal which were statistically significant (p .05) decrement in tracking and a tendency toward longer reaction times in one monitoring task during withdrawal. These performance decrements were associated with significantly lower HR (p .001) and lower (p .05) ratings of attentiveness during withdrawal from smoking. These findings support a cautious approach to the prohibition of smoking on the flight deck for aircrew members.

Key Words: Aviation environment, Simulation, Smoking withdrawal, Complex performance, Physiology, Biochemistry

No. of Pages: 16

Last updated: Friday, June 1, 2012