Guide for Aviation Medical Examiners

Special Issuances, AASI for All Classes

The Guide refers to a number of selected medical conditions that are initially disqualifying (if the applicant does not meet the issue criteria in the Aerospace Medicine Dispositions Tables or the Certification Worksheets) and must be deferred to the AMCD or RFS. If this is a first-time application for an AASI for a disqualifying disease/condition, and the applicant has all of the requisite medical information necessary for a determination, the Examiner must defer, and submit all of the documentation to the AMCD or your RFS.

Following the granting of an Authorization for Special Issuance of a Medical Certificate (Authorization) by the AMCD or RFS, an Examiner may reissue a medical certificate to an applicant with a medical history of an initially disqualifying condition once the AASI's specialized criteria is met and the applicant is otherwise qualified.

Conditions
A - GH - T
Aortic InsufficiencyHepatitis C
Arthritis and/or PsoriasisHypertension
AsthmaHyperthyroidism
Atrial FibrillationHypothyroidism
Bladder CancerLymphoma and Hodgkin's Disease
Breast CancerMelanoma
Cerebrovascular Disease (CVA/Stroke/TIA) (PDF)Migraine Headaches
Cardiac - Single Valve Replacement or RepairMitral Valve Disease (PDF)
Chronic Kidney DiseaseNeurofibromatosis Type 1 (PDF)
Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)Paroxysmal Atrial Tachycardia
Chronic Obstructive Pulmonary DiseasePrediabetes or Overweight/Obesity Treated with Medication (PDF)
Colitis (Ulcerative or Crohn's Disease) or Irritable Bowel SyndromeProstate Cancer
Colon Cancer/Colorectal CancerPsoriasis (PDF)
Coronary Heart Disease (CHD)Renal Calculi
Venous Thromboembolism (VTE) - Deep Venous Thrombosis (DVT), Pulmonary Embolism (PE), and/or HypercoagulopathiesRenal Cancer
Diabetes Mellitus - Type II Medication Controlled (Not Insulin)Sleep Apnea/Obstructive Sleep Apnea (OSA) (PDF)
GlaucomaTesticular Cancer
 Thrombocytopenia
Last updated: Wednesday, May 27, 2026