Pharmaceuticals (Therapeutic Medications)
Antidepressants

1. Code of Federal Regulations
   • First-Class Airman Medical Certificate: 67.107
   • Second-Class Airman Medical Certificate: 67.207
   • Third-Class Airman Medical Certificate: 67.307
2. Medical History
3. Aeromedical Decision Considerations
4. Protocol: As per the specific underlying condition(s)
5. Pharmaceutical Considerations:
   • Individuals exhibiting symptoms, regardless of the treatment used, must not fly.
     • Symptoms must be controlled without adverse side effects.
   
   Individuals can be considered for first, second, or third-class medical certificates while being treated with one of several specific antidepressants. The Authorization decision is made on a case-by-case basis. The AME may not issue.
   • Medications used in mental health generally have central nervous system effects and take some time to become effective, and therefore have long initial observation time considerations.
   • Underlying conditions will require a current evaluation.
   • See Use of Antidepressant Medications
   • See table of Antidepressant Medications (PDF)