- Associate Administrator for Security and Hazardous Materials Safety
- Ben Supko (Acting)
- Deputy Associate Administrator for Security and Hazardous Materials Safety
- Pete Basso (Acting)
Director, Office of National Security Programs & Incident Response- Leesa Papier
- Director, Office of Infrastructure Protection
- Pete Basso
- Director, Office of Hazardous Materials Safety
- Walter J. McBurrows (Acting)
- Director, Office of Investigations and Professional Responsibility
- Michelle Salter
- Director, Office of Business and Mission Services
- Dominique Wallace
- Director, Office of Personnel Security
- Gerald Moore
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